Idrossipropilmetilcellulosa (HPMC) Commercio all'ingrosso

Hydroxypropyl Methylcellulose (HPMC) Uses

Hydroxypropyl Methylcellulose (HPMC) is mainly derived from refined cotton/wood pulp, which is alkalized to obtain cellulose, and then added with propylene oxide and methyl chloride for etherification to obtain cellulose ether.

HPMC Cellulose act as thickener, water retaining agent, dispersant, stabilizer, emulsifier, binder, excipient, film former in various industries. HPM cellulose is widely used in construction dry-mixed mortar, pharmaceutical, petrochemical, ceramics, paper, synthetic resin, leather, food and cosmetics and other industries.

KimaCell® Hydroxypropyl Methylcellulose (HPMC) has the advantages of wide application, small unit usage, good modification effect, and environmental friendliness. HPMC products can significantly improve and optimize product performance in the field of its addition, which is conducive to improving resource utilization efficiency and product added value. Environmentally friendly additives that are essential in various fields.

1. HPMC In Pharmaceutical

In the field of medicine, Hydroxypropyl Methylcellulose (HPMC) is an important pharmaceutical excipient, which can be used in drug sustained and controlled release preparations, vegetable capsules, tablet coatings, suspending agents, tablet binders, tablet disintegrants and other application scenarios.

2. Hydroxypropyl Methyl Cellulose In Food

Food grade Hydroxypropyl Methylcellulose (HPMC) is a recognized safe food additive. It can be used as a food thickener, stabilizer and moisturizer to thicken, retain water, and improve taste. It is widely used in developed countries, mainly for baked food, collagen Protein casings, whipped cream, fruit juices, sauces, meat and other protein products, fried foods, etc. China, the United States, the European Union, and many other countries allow HPMC to be used as a food additive.

The proportion of food-grade Hydroxypropyl Methylcellulose (HPMC) used in food production in China is relatively low. The domestic market is still in the stage of application and promotion, coupled with the high price of food-grade HPMC, HPMC is used in fewer fields in food production in my country. However, with the improvement of income, the scale of the food industry is expected to maintain steady growth in the long run. Moreover, with the improvement of people's awareness of healthy food, the penetration rate of HPMC as a health additive will gradually increase. The consumption of HPMC in the food industry expected to grow further.

3. HPMC For Construction

In Construction drymix mortar industry, Hydroxypropyl Methylcellulose is used as a water-retaining agent and retarder for cement mortar to make the mortar pumpable. HPMC Used as a binder in plaster, plaster, putty powder or other building materials to improve spreadability and prolong work time. HPMC can be used as paste tile, marble, plastic decoration, paste reinforcement, and can also reduce the amount of cement. The water-retaining performance of HPMC prevents the slurry from cracking due to drying too quickly after application, and enhances the strength after hardening.

Hydroxypropyl Methylcellulose Benefits

Hydroxypropyl methylcellulose (HPMC) offers a wide range of benefits across different industries. HPMC versatile nature as thickener, stabilizer, film-former, and water-retaining agent makes it an indispensable ingredient in pharmaceuticals, food products, cosmetics, and construction materials. Whether it's providing controlled drug release in pharmaceutical formulations, improving texture and stability in food products, enhancing the performance of cosmetic formulations, or optimizing the properties of construction materials, HPMC plays a vital role.HPMC offers numerous benefits due to its unique properties, making it a valuable ingredient in many products.

• Pharmaceutical Benefits:

a. Controlled Drug Release: HPMC is commonly used as a matrix former in oral solid dosage forms, such as tablets and capsules. It provides controlled drug release, ensuring a steady and sustained release of the active pharmaceutical ingredient (API) over an extended period. This feature is particularly beneficial for drugs that require a slow release pattern to maintain therapeutic efficacy.

b. Film Coating: HPMC forms a uniform and smooth film when applied to tablets or capsules, offering protection against environmental factors such as moisture, light, and air. It also improves the appearance, swallowability, and stability of the dosage form.

c. Mucoadhesive Properties: HPMC can adhere to the mucosal surfaces, enhancing the contact time and improving drug absorption. This property is useful in the development of various oral and ocular drug delivery systems.

• Food Benefits:

a. Thickening and Stabilization: HPMC acts as a thickening and stabilizing agent in food products. It imparts viscosity, texture, and creaminess to sauces, dressings, and dairy products. It prevents phase separation and maintains the homogeneity of food formulations.

b. Fat Replacement: HPMC can be used as a fat replacer in low-fat food products. It mimics the mouthfeel and texture of fats, providing a desirable sensory experience while reducing the calorie content.

c. Water Retention: HPMC has the ability to retain water, thereby preventing moisture loss and maintaining the juiciness and freshness of food products. It is particularly useful in baked goods, where it improves shelf life and texture.

• Cosmetics Benefits:

a. Thickening and Emulsifying Agent: HPMC cellulose is widely used in cosmetic formulations, such as creams, lotions, and shampoos, due to its excellent thickening and emulsifying properties. It improves the stability and consistency of cosmetic products, allowing for better spreadability and ease of application.

b. Film-Forming: When applied to the skin or hair, HPMC cellulose forms a protective film that helps to retain moisture, reducing water loss and maintaining hydration. It also enhances the longevity of cosmetic products on the skin or hair surface.

c. Suspending Agent: HPMC can suspend solid particles in cosmetic formulations, preventing their settling or sedimentation. This property is particularly useful in suspensions, scrubs, and exfoliating products.

• Construction Benefits:

a. Cement and Mortar Additive: HPMC acts as a thickener and water-retaining agent in cement-based products, such as mortars, tile adhesives, and renders. It improves workability, adhesion, and sag resistance, while reducing cracking and shrinkage.

b. Improved Open Time: Open time refers to the duration during which a construction material remains workable after application. HPMC extends the open time of adhesives, allowing for easier positioning and adjustment of tiles, wallpapers, and other materials.

c. Water Resistance: HPMC enhances the water resistance of construction materials, making them more durable and resistant to moisture-related damage. It improves the overall performance and lifespan of buildings and structures.

Overall, the hydroxypropyl methylcellulose benefits are vast and diverse. Its multifunctional properties make it an essential ingredient in a wide range of products, providing improved performance, stability, and user experience. As research and technology continue to advance, HPMC celluloseis likely to find even more applications in various industries, further demonstrating its value and versatility.

Il processo di produzione dell'idrossipropilmetilcellulosa (HPMC) richiede diversi passaggi per modificare la cellulosa, un polimero naturale derivato da fonti vegetali. Il processo include il trattamento chimico e la reazione per l'introduzione di gruppi idrossipropilici e metilici sulla spina dorsale della cellulosa. Esploriamo il processo di produzione di HPMC nel dettaglio.

• Estrazione della cellulosa:

Il processo inizia con l'estrazione della cellulosa da fonti vegetali. Le fonti comuni includono pasta di legno, cotone o altri materiali vegetali fibrosi. La cellulosa è normalmente prodotta attraverso una serie di trattamenti meccanici e chimici, che includono la rottura del materiale vegetale e la rimozione delle impurità per ottenere un materiale di cellulosa purificata.

• Trattamento alcalino:

Una volta che la cellulosa viene estratta, viene trattata con un trattamento alcalino per rimuovere l'emicellulosa e i componenti della lignina. Questo trattamento richiede l'immersione della cellulosa in una soluzione alcalina, come l'idrossido di sodio (NaOH), per abbattere i materiali non cellulosici. Il risultato è cellulosa purificata con un grado di purezza più elevato.

• Etherification:

Il passo successivo è il processo di eterificazione, dove i gruppi idrossipropilici e metilici vengono inseriti sulla spina dorsale della cellulosa. Questo si ottiene attraverso una serie di reazioni che toccano la cellulosa e i reagenti adeguati.

Attivazione alcalina: la cellulosa purificata viene sospesa in una soluzione alcalina, in genere idrossido di sodio, per attivare la cellulosa e rendere più reattiva.

B. Idrossipropilazione: la cellulosa attivata viene quindi trattata con ossido di propilene (PO) o un composto simile. Il gruppo idrossipropilico dal PO reagisce con i gruppi idrossilici di cellulosa, leading to The attachment di gruppi idrossipropilici sulla spina dorsale di cellulosa.

C. Metilazione: seguendo la fase di idrossipropilazione, la cellulosa con i gruppi di idrossipropil attaccati viene tenuta in metilazione. Questo richiede la reazione della cellulosa idrossipropilata con cloruro di metile o un simile agente metilante. Il gruppo metilico dall'agente metilante riflette i residui gruppi idrossilici sulla cellulosa, con l'introduzione di gruppi metilici sulla spina dorsale della cellulosa.

• Neutralizzazione e lavaggio:

Dopo il processo di eterificazione, la miscela di reazione viene neutralizzata per fermare ulteriori reazioni e regolare il pH. Le soluzioni acide o di base vengono sommate per neutralizzare qualsiasi alcali o acido in eccesso presenti nella miscela. La miscela neutralizzata viene quindi lavata a fondo per rimuovere qualsiasi residuo reagenti o by-products, garantire un prodotto HPMC purificato.

• Essiccazione e fresatura:

Il passaggio finale nel processo di produzione HPMC richiede l'essiccazione e la fresatura del prodotto HPMC ottenuto. Il prodotto è in genere essiccato utilizzando metodi di asciugatura ad aria calda o sottovuoto per rimuovere l'umidità e ottenere una polvere secca. L'hpmc essiccato viene fresato per raggiungere la dimensione e l'uniforme delle particelle richieste, con una polvere fine pronta per l'imballaggio e la distribuzione.

Vale la pena osservare che il processo di produzione specifico di HPMC può cambiare leggermente tra i diversi produttori e i loro metodi di proprietà. I principi e i passaggi generali inclusi nel processo continuano ad essere coerenti.

In fine, il processo di produzione dell'idrossipropilmetilcellulosa (HPMC) richiede l'estrazione della cellulosa da fonti vegetali, seguito dal trattamento degli alcali, attivazione degli alcali, idrossipropilazione, metilazione, neutralizzazione, lavaggio, asciugatura, E fresatura. Questo processo produce la produzione di HPMC, un composto versatile con varie applicazioni in settori come prodotti farmaceutici, alimenti, cosmetici e costruzioni.